Endocrine Abstracts

Background: Prader-Willi syndrome (PWS) is the most frequent genetic cause of obesity and is often complicated by glucose metabolism alterations. Conventional therapies prescribed in type 2 diabetes mellitus (T2DM), like oral hypoglycemic agents and insulin, frequently failed to achieve adequate glycemic control in patients with PWS. Beneficial effects of the glucagon like peptide-1 receptor agonists (GLP1RAs) exenatide and liraglutide have been reported for the management of ...

Introduction: Wernicke’s encephalopathy, resulting from thiamine deficiency, is a rare but serious neurological complication of bariatric procedures. The diagnosis is still difficult since the classic clinical triad (confusion, ataxia and oculomotor abnormalities) and the typical radiological features (areas of hyperintensity in mammillary bodies, thalamus, periaqueductal and periventricular gray matter) are not always present. Also, thiamine blood tests are not broadly a...